The Challenges

• Resists chemotherapy, radiation and other therapies because the brain has a tough barrier that prevents access to the tumor. Treatments that are able to break through are then also actively blocked by the tumor.
• Defies surgery because it interweaves with healthy brain tissue.

• Mutates and changes its identity to develop a resistance to therapies.
• Varies widely, making it extremely difficult to replicate in a lab or find a single cure.
• Attacks brain function, so it heartbreakingly impacts patients’ ability to move, speak, see or think.
• Grows extremely rapidly and aggressively.

New Developments

• Development of ERAS-801, a promising new medication designed to hinder tumor growth, which is currently in a new clinical trial.Treatments that are able to break through are then also actively blocked by the tumor.
• Breakthrough discovery that Glioblastoma uniquely has two molecular blocks that thwart therapy. New treatment is now being tested to take down one of the blocks.

• Groundbreaking “one-stop” research model that identifies the target, creates the drug, evaluates tumor response, and then quickly iterates – all onsite, for greater precision and efficiency. This tight research loop is conducted on multiple targets at the same time for exponential learning – and higher odds for effective outcomes.
• New equipment that enables onsite research, making funds go further and discovery move faster.
• An expanding team of experts that drive world-class drug discovery and research. Namely, renowned chemist, Dr. Alan Olivero has joined the team to lead drug discovery, bringing extensive pharmaceutical company experience.

Your Impact

• Enabling the nation’s leading researchers the funds they need to continue moving the needle.
• Thanks to your donations and the Stanford L. Kurland Fund, there has been major strides in the understanding, research, and treatments for Glioblastoma.
• Your donation has a tangible impact on Dr. Timothy Cloughesy, M.D., and Dr. David Nathanson, Ph.D.’s efforts in finding a cure.

Donate Here →